Dr. Alper Karagöl is a medical doctor and incoming MIT Postdoctoral Fellow who specializes in advanced protein engineering and molecular circuit design. His foundational research focuses on developing environment-responsive therapeutics, supported by a portfolio of over thirty publications and featured cover articles that leverage his expertise in protein engineering. In addition to his molecular work, he constructs complex mathematical models for genomic and epidemiological datasets to analyze health challenges. As a biotechnology entrepreneur, he actively bridges these computational disciplines to translate structural and population-level insights into practical clinical solutions.

I am experienced in non-parametric statistical tests and correlation analysis including non-linear analysis and Kernel regression methods for orthologous sequences generated by Hidden Markov models (HMM). I use an alternative approach by analyzing the Nash Equilibrium (NE) of the Evolutionary Stable Strategy, without an explicit solution to complex dynamics. For physics-based approaches, I utilize Gibbs free energy calculations considering attractive contributions to the van der Waals interaction energy. I conduct Molecular Dynamics Simulations and Multimer Predictions for both globular and membranous proteins. For the intensive calculations, I am familiar with various supercomputer infrastructures including Google Compute Engine and Colab.